Madecassic acid with CAS 18449-41-7

Products Details

What is Madecassic acid with CAS 18449-41-7?

Specification of Madecassic acid with CAS 18449-41-7

CAS 18449-41-7
Names Madecassic acid
Appearance Powder
Purity 98%
MF C30H48O6
Grade Food $ Medical Grade
Package 25kgs/bag,20tons/20’container
Brand Name Unilong
Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; Item No. 14010), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; Item No. 13104). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.

Application of Madecassic acid with CAS 18449-41-7

Madecassic Acid is a terpenoid with an ursane skeleton isolated from Centella asiatica. Madecassic Acid displays anti-inflammatory properties as a result of iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 inhibition via the downregulation of NF-kappaB activation in RAW 264.7 macrophage cells.

Packing  of Madecassic acid with CAS 18449-41-7

25kgs/drum,9tons/20'container 25kgs/bag,20tons/20'container

odium-dodecylbenzenesulphonate

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